Three-Component Coupling of Arynes, Aminosilanes, and Aldehydes.
نویسندگان
چکیده
منابع مشابه
Aminosilylation of arynes with aminosilanes: synthesis of 2-silylaniline derivatives.
The nitrogen-silicon sigma-bond of aminosilanes added across the triple bond of arynes to give varied 2-silylaniline derivatives straightforwardly.
متن کاملThree-component coupling reactions of arynes for the synthesis of benzofurans and coumarins.
The domino three-component coupling reaction of arynes with DMF and active methylenes or methines was studied as a highly efficient method for preparing heterocycles. Coumarin derivative 5 was formed when diethyl malonate (2) or α-bromomalonate (3) were used as a C2-unit. In contrast, dihydrobenzofurans 7a and 7b were obtained by using α-chloroenolates generated from α-chloromalonates 4a and 4b...
متن کاملCopper-catalyzed three-component coupling of arynes, terminal alkynes and activated alkenes.
The three-component coupling of benzynes with terminal alkynes and activated alkenes in the presence of CuI, PCy(3) and CsF in a 1:1 mixture of CH(3)CN and THF at 50 degrees C for 5 h gave 1-alkyl-2-alkynylbenzenes in good to moderate yields.
متن کاملThree-component coupling using arynes and DMF: straightforward access to coumarins via ortho-quinone methides.
ortho-Quinone methides, arising from a formal [2+2] cycloaddition between arynes and DMF, were found to facilely undergo a [4+2] cycloaddition with ester enolates or ketenimine anions to produce diverse coumarins in a straightforward manner.
متن کاملMulticomponent reactions involving phosphines, arynes and aldehydes.
Although nucleophilic phosphine-catalysis is a powerful tool for the construction of various carbocycles and heterocycles, the reactions in which phosphines are incorporated into the final product are rare, and the reports on phosphine addition to highly electrophilic arynes are scarce. Herein, we report the phosphine triggered multicomponent reaction of arynes and aldehydes, which takes place ...
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ژورنال
عنوان ژورنال: ChemInform
سال: 2007
ISSN: 0931-7597,1522-2667
DOI: 10.1002/chin.200752080